hMailServer

In addition hMailServer is a free, open source, e-mail server for Microsoft Windows. Hence it’s used by Internet service providers, companies, governments in all parts of the world. It also supports the common e-mail protocols (IMAP, SMTP and POP3) and can easily be integrated with many existing web mail systems. Therefore It has flexible score-based spam protection. Likewise it  can attach to your virus scanner to scan all incoming and outgoing email.
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Free & Open Source

In addition license under AGPLV3, hMAILSERVER can be used for free in most commercial scenarios. It’s source codes is available for anyone to read or extent at GitHub though.

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Build-in Anti-Spam

In general hMAILSERVER comes with set of built-in anti-spam features such as SPF, SURBL. It can also be integrated with 3rd party anti-spam systems such as SpamAssassin, ASSP.

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Webmail

As a matter of fact any webmail system which supports IMAP and SMTP can be used with hMAILSERVER. Similarly RoundCube and SquirrelMail are popular web-mail systems.